Amyloid PET in the diagnostic workup of neurodegenerative disease

Several radiotracers have been employed to bind amyloid plaques in the brain for differential diagnosis of neurodegenerative disease, open possibility measure vivo pathogenic processes implicated Alzheimer disease (AD) and potential detect at earliest stages with a role clinical trials’ longitudinal assessment. Visual reading is clinically adequate clearly positive or negative cases but adoption validated standardized quantification methods amyloid-PET diagnose AD research settings has become essential. The present Pictorial Essay presenting case series nine patients describes current amy-PET imaging elucidating typical assessment, possible artifacts pitfalls occurring scenario, focusing also on development diagnostic workup disease.